The Zimbra web interface has a cool search folder feature, just like Thunderbird or Outlook, it allows you to specify search criteria, and then save them as a virtual email folder. Every time you go to this folder, the search you specified is performed, and the results are shown in this folder. For people with huge mailboxes, this is a really good thing!
A simple but really useful one is "unread":
You can now use this in the web interface, as well as subscribe to it in your mail application if you need to use that. In thunderbird:
Outlook is pretty similar:
Have a play with the other search options as well, its a nice way to build up searches